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Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

Ferroptosis is a cell death process driven by damage to cell membranes and linked to numerous human diseases. Ferroptosis is caused by loss of activity of the key enzyme that is tasked with repairing oxidative damage to cell membranes—glutathione peroxidase 4 (GPX4). GPX4 normally removes the danger...

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Detaylı Bibliyografya
Yayımlandı:PLoS Biol
Asıl Yazarlar: Feng, Huizhong, Stockwell, Brent R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991413/
https://ncbi.nlm.nih.gov/pubmed/29795546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006203
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