Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers

Although radiation is widely used to treat cancers, resistance mechanisms often develop and involve activation of DNA repair and inhibition of apoptosis. Therefore, compounds that sensitize cancer cells to radiation via alternative cell death pathways are valuable. We report here that ferroptosis, a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Chem Biol
मुख्य लेखकों: Ye, Ling F., Chaudhary, Kunal R., Zandkarimi, Fereshteh, Harken, Andrew D., Kinslow, Connor J., Upadhyayula, Pavan S., Dovas, Athanassios, Higgins, Dominique M., Tan, Hui, Zhang, Yan, Buonanno, Manuela, Wang, Tony J. C., Hei, Tom K., Bruce, Jeffrey N., Canoll, Peter D., Cheng, Simon K., Stockwell, Brent R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180072/
https://ncbi.nlm.nih.gov/pubmed/31899616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00939
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