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Ferroptosis: death by lipid peroxidation

Ferroptosis is a regulated form of cell death driven by loss of activity of the lipid repair enzyme glutathione peroxidase 4 (GPX4) and subsequent accumulation of lipid-based reactive oxygen species, particularly lipid hydroperoxides. This form of iron-dependent cell death is genetically, biochemica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Cell Biol
Prif Awduron: Yang, Wan Seok, Stockwell, Brent R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764384/
https://ncbi.nlm.nih.gov/pubmed/26653790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.10.014
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