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Breakdown of an ironclad defense system: The critical role of NRF2 in mediating ferroptosis

Ferroptosis is a non-apoptotic mode of regulated cell death that is iron- and lipid peroxidation-dependent. As new mechanistic insight into ferroptotic effectors and how they are regulated in different disease contexts is uncovered, our understanding of the physiological and pathological relevance o...

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Pubblicato in:Cell Chem Biol
Autori principali: Anandhan, Annadurai, Dodson, Matthew, Schmidlin, Cody J., Liu, Pengfei, Zhang, Donna D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7597851/
https://ncbi.nlm.nih.gov/pubmed/32275864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.03.011
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