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Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq

Phosphoenolpyruvate carboxykinase 1 (PCK1), a step limiting enzyme of gluconeogenesis, is downregulated in hepatocellular carcinoma (HCC). Overexpression of PCK1 has been shown to suppress hepatoma cell growth, but the underlying mechanism remains unclear. We used recombinant adenovirus overexpressi...

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Détails bibliographiques
Publié dans:Genes Dis
Auteurs principaux: Xiang, Jin, Zhang, Yuhong, Tuo, Lin, Liu, Rui, Gou, Dongmei, Liang, Li, Chen, Chang, Xia, Jie, Tang, Ni, Wang, Kai
Format: Artigo
Langue:Inglês
Publié: Chongqing Medical University 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063442/
https://ncbi.nlm.nih.gov/pubmed/32181286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.04.004
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