The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle

The mitochondrial Ca(2+) uniporter (MCU) complex mediates acute mitochondrial Ca(2+) influx. In skeletal muscle, MCU links Ca(2+) signaling to energy production by directly enhancing the activity of key metabolic enzymes in the mitochondria. Here, we examined the role of MCU in skeletal muscle devel...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Kwong, Jennifer Q., Huo, Jiuzhou, Bround, Michael J., Boyer, Justin G., Schwanekamp, Jennifer A., Ghazal, Nasab, Maxwell, Joshua T., Jang, Young C., Khuchua, Zaza, Shi, Kevin, Bers, Donald M., Davis, Jennifer, Molkentin, Jeffery D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302934/
https://ncbi.nlm.nih.gov/pubmed/30429366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121689
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki