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Voltage-dependent dynamics of the BK channel cytosolic gating ring are coupled to the membrane-embedded voltage sensor

In humans, large conductance voltage- and calcium-dependent potassium (BK) channels are regulated allosterically by transmembrane voltage and intracellular Ca(2+). Divalent cation binding sites reside within the gating ring formed by two Regulator of Conductance of Potassium (RCK) domains per subuni...

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Vydáno v:eLife
Hlavní autoři: Miranda, Pablo, Holmgren, Miguel, Giraldez, Teresa
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301790/
https://ncbi.nlm.nih.gov/pubmed/30526860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40664
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