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State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels
Large-conductance voltage- and calcium-dependent potassium channels (BK, “Big K+”) are important controllers of cell excitability. In the BK channel, a large C-terminal intracellular region containing a “gating-ring” structure has been proposed to transduce Ca(2+) binding into channel opening. Using...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612663/ https://ncbi.nlm.nih.gov/pubmed/23479636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219611110 |
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