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Compromised regulation of the collecting duct ENaC activity in mice lacking AT(1a) receptor
ENaC-mediated sodium reabsorption in the collecting duct (CD) is a critical determinant of urinary sodium excretion. Existing evidence suggest direct stimulatory actions of Angiotensin II (Ang II) on ENaC in the CD, independently of the aldosterone- mineralocorticoid receptor (MR) signaling. Deletio...
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| Pubblicato in: | J Cell Physiol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6301083/ https://ncbi.nlm.nih.gov/pubmed/29574718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26552 |
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