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Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling

PURPOSE OF REVIEW: Locally produced peptide hormones kinins, such as bradykinin, are thought to oppose many of the prohypertensive actions of the renin–angiotensin–aldosterone system. In the kidney, bradykinin, via stimulation of B2 receptors (B2R), favors natriuresis mostly due to the inhibition of...

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Autori principali: Mamenko, Mykola, Zaika, Oleg, Pochynyuk, Oleh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114036/
https://ncbi.nlm.nih.gov/pubmed/24378775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.mnh.0000441053.81339.61
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