Bradykinin acutely inhibits activity of the epithelial Na(+) channel in mammalian aldosterone-sensitive distal nephron

Activation of the renal kallikrein-kinin system results in natriuresis and diuresis, suggesting its possible role in renal tubular sodium transport regulation. Here, we used patch-clamp electrophysiology to directly assess the effects of bradykinin (BK) on the epithelial Na(+) channel (ENaC) activit...

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Bibliographic Details
Main Authors: Zaika, Oleg, Mamenko, Mykola, O'Neil, Roger G., Pochynyuk, Oleh
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094057/
https://ncbi.nlm.nih.gov/pubmed/21325499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00606.2010
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