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Compromised regulation of the collecting duct ENaC activity in mice lacking AT(1a) receptor
ENaC-mediated sodium reabsorption in the collecting duct (CD) is a critical determinant of urinary sodium excretion. Existing evidence suggest direct stimulatory actions of Angiotensin II (Ang II) on ENaC in the CD, independently of the aldosterone- mineralocorticoid receptor (MR) signaling. Deletio...
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| 出版年: | J Cell Physiol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6301083/ https://ncbi.nlm.nih.gov/pubmed/29574718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26552 |
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