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Compromised regulation of the collecting duct ENaC activity in mice lacking AT(1a) receptor

ENaC-mediated sodium reabsorption in the collecting duct (CD) is a critical determinant of urinary sodium excretion. Existing evidence suggest direct stimulatory actions of Angiotensin II (Ang II) on ENaC in the CD, independently of the aldosterone- mineralocorticoid receptor (MR) signaling. Deletio...

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Dades bibliogràfiques
Publicat a:J Cell Physiol
Autors principals: Mamenko, Mykola, Zaika, Oleg, Tomilin, Viktor, Jensen, V.BehraNa, Pochynyuk, Oleh
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301083/
https://ncbi.nlm.nih.gov/pubmed/29574718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26552
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