Tissue and species differences in the glucuronidation of glabridin with UDP-glucuronosyltransferases

Glabridin (GA) has gained wide application in the cosmetics and food industry. This study was performed to investigate its metabolic inactivation and elimination by glucuronidation by use of liver and intestine microsomes from humans (HLM and HIM) and rats (RLM and RIM), and liver microsomes from cy...

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Veröffentlicht in:Chem Biol Interact
Hauptverfasser: Guo, Bin, Fang, Zhongze, Yang, Lu, Xiao, Ling, Xia, Yangliu, Gonzalez, Frank J., Zhu, Liangliang, Cao, Yunfeng, Ge, Guangbo, Yang, Ling, Sun, Hongzhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300978/
https://ncbi.nlm.nih.gov/pubmed/25765239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2015.03.001
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