Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha

Activated invariant natural killer T (iNKT) cells rapidly produce large amounts of cytokines, but how cytokine mRNAs are induced, stabilized and mobilized following iNKT activation is still unclear. Here we show that an endoplasmic reticulum stress sensor, inositol-requiring enzyme 1α (IRE1α), links...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Govindarajan, Srinath, Gaublomme, Djoere, Van der Cruyssen, Renée, Verheugen, Eveline, Van Gassen, Sofie, Saeys, Yvan, Tavernier, Simon, Iwawaki, Takao, Bloch, Yehudi, Savvides, Savvas. N., Lambrecht, Bart N., Janssens, Sophie, Elewaut, Dirk, Drennan, Michael B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297233/
https://ncbi.nlm.nih.gov/pubmed/30559399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07758-x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker