NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20

Natural killer T (NKT) cells are innate lymphocytes that differentiate into NKT1, NKT2, and NKT17 sublineages during development. However, the signaling events that control NKT sublineage specification and differentiation remain poorly understood. Here, we demonstrate that the ubiquitin-modifying en...

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Drennan, Michael B., Govindarajan, Srinath, Verheugen, Eveline, Coquet, Jonathan M., Staal, Jens, McGuire, Conor, Taghon, Tom, Leclercq, Georges, Beyaert, Rudi, van Loo, Geert, Lambrecht, Bart N., Elewaut, Dirk
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2016
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030796/
https://ncbi.nlm.nih.gov/pubmed/27551157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151065
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