NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20

Natural killer T (NKT) cells are innate lymphocytes that differentiate into NKT1, NKT2, and NKT17 sublineages during development. However, the signaling events that control NKT sublineage specification and differentiation remain poorly understood. Here, we demonstrate that the ubiquitin-modifying en...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Drennan, Michael B., Govindarajan, Srinath, Verheugen, Eveline, Coquet, Jonathan M., Staal, Jens, McGuire, Conor, Taghon, Tom, Leclercq, Georges, Beyaert, Rudi, van Loo, Geert, Lambrecht, Bart N., Elewaut, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030796/
https://ncbi.nlm.nih.gov/pubmed/27551157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151065
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