NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20

Natural killer T (NKT) cells are innate lymphocytes that differentiate into NKT1, NKT2, and NKT17 sublineages during development. However, the signaling events that control NKT sublineage specification and differentiation remain poorly understood. Here, we demonstrate that the ubiquitin-modifying en...

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Vydáno v:J Exp Med
Hlavní autoři: Drennan, Michael B., Govindarajan, Srinath, Verheugen, Eveline, Coquet, Jonathan M., Staal, Jens, McGuire, Conor, Taghon, Tom, Leclercq, Georges, Beyaert, Rudi, van Loo, Geert, Lambrecht, Bart N., Elewaut, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030796/
https://ncbi.nlm.nih.gov/pubmed/27551157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151065
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