Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice

Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, highcarbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compared hippocampus biology and memory in mice subjected to 20% CR or provi...

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Udgivet i:Cell Rep
Main Authors: Wahl, Devin, Solon-Biet, Samantha M., Wang, Qiao-Ping, Wali, Jibran A., Pulpitel, Tamara, Clark, Ximonie, Raubenheimer, David, Senior, Alistair M., Sinclair, David A., Cooney, Gregory J., de Cabo, Rafael, Cogger, Victoria C., Simpson, Stephen J., Le Couteur, David G.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296764/
https://ncbi.nlm.nih.gov/pubmed/30463018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.070
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