Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors

Rivastigmine (Riv) is a potent and selective cholinesterase (acetylcholinesterase, AChE and butyrylcholinesterase, BuChE) inhibitor developed for the treatment of Alzheimer’s disease (AD). To elucidate whether Riv causes neuronal differentiation, we examined its effect on nerve growth factor (NGF)-i...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Terada, Kazuki, Migita, Keisuke, Matsushima, Yukari, Sugimoto, Yumi, Kamei, Chiaki, Matsumoto, Taichi, Mori, Masayoshi, Matsunaga, Kazuhisa, Takata, Jiro, Karube, Yoshiharu
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296549/
https://ncbi.nlm.nih.gov/pubmed/30557385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209250
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