Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors

Rivastigmine (Riv) is a potent and selective cholinesterase (acetylcholinesterase, AChE and butyrylcholinesterase, BuChE) inhibitor developed for the treatment of Alzheimer’s disease (AD). To elucidate whether Riv causes neuronal differentiation, we examined its effect on nerve growth factor (NGF)-i...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Terada, Kazuki, Migita, Keisuke, Matsushima, Yukari, Sugimoto, Yumi, Kamei, Chiaki, Matsumoto, Taichi, Mori, Masayoshi, Matsunaga, Kazuhisa, Takata, Jiro, Karube, Yoshiharu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296549/
https://ncbi.nlm.nih.gov/pubmed/30557385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209250
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