Prodrugs for Skin Delivery of Menahydroquinone-4, an Active Form of Vitamin K(2(20)), Could Overcome the Photoinstability and Phototoxicity of Vitamin K(2(20))

The effective delivery of menahydroquinone-4 (MKH), an active form of menaquinone-4 (MK-4, vitamin K(2(20))), to the skin is beneficial in the treatment of various skin pathologies. However, its delivery through the application of MK-4 to the skin is hampered due to the photoinstability and phototox...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Goto, Shotaro, Setoguchi, Shuichi, Yamakawa, Hirofumi, Watase, Daisuke, Terada, Kazuki, Matsunaga, Kazuhisa, Karube, Yoshiharu, Takata, Jiro
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566782/
https://ncbi.nlm.nih.gov/pubmed/31137618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102548
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