Genome wide association study to identify predictors for severe skin toxicity in colorectal cancer patients treated with cetuximab

EGFR-antibodies are associated with significant skin toxicity, including acneiform rash and folliculitis. It remains impossible to predict the occurrence of severe skin toxicity due to the lack of predictive markers. Here, we present the first genome-wide association study (GWAS) to find single nucl...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Baas, Jara, Krens, Lisanne, Bohringer, Stefan, Mol, Linda, Punt, Cornelis, Guchelaar, Henk-Jan, Gelderblom, Hans
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296548/
https://ncbi.nlm.nih.gov/pubmed/30557370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208080
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