Genome Wide Association Study for Predictors of Progression Free Survival in Patients on Capecitabine, Oxaliplatin, Bevacizumab and Cetuximab in First-Line Therapy of Metastatic Colorectal Cancer

PURPOSE: Despite expanding options for systemic treatment, survival for metastatic colorectal cancer (mCRC) remains limited and individual response is difficult to predict. In search of pre-treatment predictors, pharmacogenetic research has mainly used a candidate gene approach. Genome wide associat...

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Vydáno v:PLoS One
Hlavní autoři: Pander, Jan, van Huis-Tanja, Lieke, Böhringer, Stefan, van der Straaten, Tahar, Gelderblom, Hans, Punt, Cornelis, Guchelaar, Henk-Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519298/
https://ncbi.nlm.nih.gov/pubmed/26222057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131091
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