Genome wide association study to identify predictors for severe skin toxicity in colorectal cancer patients treated with cetuximab

EGFR-antibodies are associated with significant skin toxicity, including acneiform rash and folliculitis. It remains impossible to predict the occurrence of severe skin toxicity due to the lack of predictive markers. Here, we present the first genome-wide association study (GWAS) to find single nucl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Baas, Jara, Krens, Lisanne, Bohringer, Stefan, Mol, Linda, Punt, Cornelis, Guchelaar, Henk-Jan, Gelderblom, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296548/
https://ncbi.nlm.nih.gov/pubmed/30557370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208080
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