Concordance of Predictive Markers for EGFR Inhibitors in Primary Tumors and Metastases in Colorectal Cancer: A Review

BACKGROUND. Currently, only Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) mutational status is used as a decisional marker for epidermal growth factor receptor (EGFR) inhibitor therapy in colorectal cancer (CRC) patients. Concordance of KRAS status between primary tumors and metastases has alw...

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Detalhes bibliográficos
Main Authors: Baas, Jara M., Krens, Lisanne L., Guchelaar, Henk-Jan, Morreau, Hans, Gelderblom, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2011
Assuntos:
Gastrointestinal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228174/
https://ncbi.nlm.nih.gov/pubmed/21742964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0024
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