High-fat diet-induced obesity and insulin resistance in CYP4a14(−/−) mice is mediated by 20-HETE

20-Hydroxyeicosatetraenoic acid (20-HETE) has been shown to positively correlate with body mass index, hyperglycemia, and plasma insulin levels. This study seeks to identify a causal relationship between 20-HETE and obesity-driven insulin resistance. Cyp4a14(−/−) male mice, a model of 20-HETE overpr...

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Bibliografske podrobnosti
izdano v:Am J Physiol Regul Integr Comp Physiol
Main Authors: Gilani, Ankit, Pandey, Varunkumar, Garcia, Victor, Agostinucci, Kevin, Singh, Shailendra P., Schragenheim, Joseph, Bellner, Lars, Falck, John R., Paudyal, Mahesh P., Capdevila, Jorge H., Abraham, Nader G., Laniado Schwartzman, Michal
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295494/
https://ncbi.nlm.nih.gov/pubmed/30088983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00125.2018
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