20-HETE Interferes with Insulin Signaling and Contributes to Obesity-Driven Insulin Resistance

20-HETE, a metabolite of arachidonic acid produced by Cytochrome P450 (CYP) 4A/4F, has been implicated in the development of obesity-associated complications such as diabetes and insulin resistance. In this study, we examined whether the acute elevation of 20-HETE levels contributes to the developme...

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Detalhes bibliográficos
Publicado no:Prostaglandins Other Lipid Mediat
Main Authors: Gilani, Ankit, Agostinucci, Kevin, Hossain, Sakib, Pascale, Jonathan V., Garcia, Victor, Michael Adebesin, Adeniyi, Falck, John R., Schwartzman, Michal Laniado
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855891/
https://ncbi.nlm.nih.gov/pubmed/33011364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2020.106485
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