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20-HETE in the regulation of vascular and cardiac function

20-HETE, the ω-hydroxylation product of arachidonic acid catalyzed by enzymes of the cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent effects on the vasculature including stimulation of smooth muscle cell contractility, migration and proliferation as well as a...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Rocic, Petra, Schwartzman, Michal Laniado
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278600/
https://ncbi.nlm.nih.gov/pubmed/30048707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2018.07.004
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