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20-HETE in the regulation of vascular and cardiac function
20-HETE, the ω-hydroxylation product of arachidonic acid catalyzed by enzymes of the cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent effects on the vasculature including stimulation of smooth muscle cell contractility, migration and proliferation as well as a...
Enregistré dans:
| Publié dans: | Pharmacol Ther |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6278600/ https://ncbi.nlm.nih.gov/pubmed/30048707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2018.07.004 |
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