Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE

We have previously reported that adenoviral-mediated delivery of cytochrome P-450 (CYP) 4A2, which catalyzes the synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE), results in endothelial dysfunction and hypertension in Sprague-Dawley (SD) rats (Wang JS, Singh H, Zhang F, Ishizuka T, Deng H, Kem...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Inoue, Kazuyoshi, Sodhi, Komal, Puri, Nitin, Gotlinger, Katherine H., Cao, Jiang, Rezzani, Rita, Falck, John R., Abraham, Nader G., Laniado-Schwartzman, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775578/
https://ncbi.nlm.nih.gov/pubmed/19675180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00364.2009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados