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The on-fibrillation-pathway membrane content leakage and off-fibrillation-pathway lipid mixing induced by 40-residue β-amyloid peptides in biologically relevant model liposomes
Disruption of the synaptic plasma membrane (SPM) induced by the aggregation of β-amyloid (Aβ) peptides has been considered as a potential mechanism for the neurotoxicity of Aβ in Alzheimer’s disease (AD). However, the molecular basis of such membrane disruption process remains unclear, mainly becaus...
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| Publicado no: | Biochim Biophys Acta Biomembr |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295276/ https://ncbi.nlm.nih.gov/pubmed/29548698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2018.03.008 |
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