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Fibrillization of 40-Residue β-Amyloid Peptides in Membrane-Like Environments Leads to Different Fibril Structures and Reduced Molecular Polymorphisms

The molecular-level polymorphism in β-Amyloid (Aβ) fibrils have recently been considered as a pathologically relevant factor in Alzheimer’s disease (AD). Studies showed that the structural deviations in human-brain-seeded Aβ fibrils potentially correlated with the clinical histories of AD patients....

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書誌詳細
主要な著者: Qinghui Cheng, Zhi-Wen Hu, Yuto Tobin-Miyaji, Amy E. Perkins, Terrence Deak, Wei Qiang
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2020-06-01
シリーズ:Biomolecules
主題:
オンライン・アクセス:https://www.mdpi.com/2218-273X/10/6/881
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