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Time-dependent Lipid Dynamics, Organization and Peptide-Lipid Interaction in Phospholipid Bilayers with Incorporated β-Amyloid Oligomers

Non-fibrillar β-amyloid (Aβ) oligomers are considered as major neurotoxic species in the pathology of Alzheimer’s disease (AD). The presence of Aβ oligomers were shown to cause membrane disruptions in a broad range of model systems. However, the molecular basis of such disruption process remains unk...

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Bibliographische Detailangaben
Veröffentlicht in:J Phys Chem Lett
Hauptverfasser: Qiang, Wei, Doherty, Katelynne E., Klees, Lukas M., Tobin-Miyaji, Yuto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647725/
https://ncbi.nlm.nih.gov/pubmed/32931283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.0c01967
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