Modeling Amyloid β-Peptide Insertion into Lipid Bilayers

Inspired by recent suggestions that the Alzheimer's amyloid β peptide (Aβ) can insert into cell membranes and form harmful ion channels, we model insertion of the 40- and 42-residue forms of the peptide into cell membranes using a Monte Carlo code which is specific at the amino acid level. We e...

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Bibliografiske detaljer
Main Authors: Mobley, David L., Cox, Daniel L., Singh, Rajiv R. P., Maddox, Michael W., Longo, Marjorie L.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2004
Fag:
Biophysical Theory and Modeling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304261/
https://ncbi.nlm.nih.gov/pubmed/15189856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.032342
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