The N-terminal modified Aβ variants enable modulations to the structures and cytotoxicity levels of wild-type Aβ fibrils through cross-seeding

por Hu, Zhi-Wen, Au, Dan Fai, Cruceta, Letticia, Vugmeyster, Liliya, Qiang, Wei
Publicado no ACS Chem Neurosci (2020)

The on-fibrillation-pathway membrane content leakage and off-fibrillation-pathway lipid mixing induced by 40-residue β-amyloid peptides in biologically relevant model liposomes

por Cheng, Qinghui, Hu, Zhi-Wen, Doherty, Katelynne E., Tobin-Miyaji, Yuto J., Qiang, Wei
Publicado no Biochim Biophys Acta Biomembr (2018)

Molecular structure of an N-terminal phosphorylated β-amyloid fibril

por Hu, Zhi-Wen, Vugmeyster, Liliya, Au, Dan Fai, Ostrovsky, Dmitry, Sun, Yan, Qiang, Wei
Publicado no Proc Natl Acad Sci U S A (2019)

Phosphorylation induces distinct alpha-synuclein strain formation

por Ma, Meng-Rong, Hu, Zhi-Wen, Zhao, Yu-Fen, Chen, Yong-Xiang, Li, Yan-Mei
Publicado no Sci Rep (2016)

Fibrillization of 40-residue β-Amyloid Peptides in Membrane-Like Environments Leads to Different Fibril Structures and Reduced Molecular Polymorphisms

por Cheng, Qinghui, Hu, Zhi-Wen, Tobin-Miyaji, Yuto, Perkins, Amy E., Deak, Terrence, Qiang, Wei
Publicado no Biomolecules (2020)

Effect of Post-Translational Modifications and Mutations on Amyloid-β Fibrils Dynamics at N Terminus

por Vugmeyster, Liliya, Au, Dan F., Ostrovsky, Dmitry, Kierl, Brian, Fu, Riqiang, Hu, Zhi-wen, Qiang, Wei
Publicado no Biophys J (2019)

Phosphorylation at Ser(8) as an Intrinsic Regulatory Switch to Regulate the Morphologies and Structures of Alzheimer's 40-residue β-Amyloid (Aβ40) Fibrils

por Hu, Zhi-Wen, Ma, Meng-Rong, Chen, Yong-Xiang, Zhao, Yu-Fen, Qiang, Wei, Li, Yan-Mei
Publicado no J Biol Chem (2017)

Phosphorylation at Ser(8) as an intrinsic regulatory switch to regulate the morphologies and structures of Alzheimer's 40-residue β-amyloid (Aβ40) fibrils.

por Hu, Zhi-Wen, Ma, Meng-Rong, Chen, Yong-Xiang, Zhao, Yu-Fen, Qiang, Wei, Li, Yan-Mei
Publicado no J Biol Chem (2017)

Selective inhibition of cancer cells by enzyme-induced gain of function of phosphorylated melittin analogues

por Li, Qian-Qian, Chen, Pu-Guang, Hu, Zhi-Wen, Cao, Yuan, Chen, Liang-Xiao, Chen, Yong-Xiang, Zhao, Yu-Fen, Li, Yan-Mei
Publicado no Chem Sci (2017)