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The N-terminal modified Aβ variants enable modulations to the structures and cytotoxicity levels of wild-type Aβ fibrils through cross-seeding
Post-translational modifications (PTMs) of β-amyloid (Aβ) peptides are considered as triggering factors in sporadic Alzheimer’s diseases. However, studies to show the influences of pre-existed PTM-Aβ fibrils on wild-type Aβ peptides, which directly mimic the triggering scenarios, are rare. Here we s...
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| Publicado no: | ACS Chem Neurosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7647724/ https://ncbi.nlm.nih.gov/pubmed/32603584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00316 |
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