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Dynamics of Serine-8 Side-chain in Amyloid-β fibrils and Fluorenylmethyloxycarbonyl Serine Amino Acid, Investigated by Solid-State Deuteron NMR

Serine side-chains are strategic sites of post-translational modifications and it is important to establish benchmarks of their internal dynamics. In this work we compare the dynamics of serine side-chains in several biologically important systems: Serine-8 in the disordered domain of Aβ(1–40) fibri...

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Publicat a:J Phys Chem B
Autors principals: Vugmeyster, Liliya, Au, Dan Fai, Ostrovsky, Dmitry, Rickertsen, Dillon Ray Lee, Reed, Scott M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875318/
https://ncbi.nlm.nih.gov/pubmed/32396356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c02490
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