Thioredoxin overexpression in both the cytosol and mitochondria accelerates age-related disease and shortens lifespan in male C57BL/6 mice

To investigate the role of increased levels of thioredoxin (Trx) in both the cytosol (Trx1) and mitochondria (Trx2) on aging, we have conducted a study to examine survival and age-related diseases using male mice overexpressing Trx1 and Trx2 (TXNTg × TXN2Tg). Our study demonstrated that the upregula...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:GeroScience
Asıl Yazarlar: Cunningham, Geneva M., Flores, Lisa C., Roman, Madeline G., Cheng, Christie, Dube, Sara, Allen, Colton, Valentine, Joseph M., Hubbard, Gene B., Bai, Yidong, Saunders, Thomas L., Ikeno, Yuji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2018
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294725/
https://ncbi.nlm.nih.gov/pubmed/30121784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-018-0039-6
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller