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Flexibility and structure of flanking DNA impact transcription factor affinity for its core motif
Spatial and temporal expression of genes is essential for maintaining phenotype integrity. Transcription factors (TFs) modulate expression patterns by binding to specific DNA sequences in the genome. Along with the core binding motif, the flanking sequence context can play a role in DNA–TF recogniti...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294565/ https://ncbi.nlm.nih.gov/pubmed/30395339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1057 |
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