Shared nucleotide flanks confer transcriptional competency to bZip core motifs

Sequence-specific DNA binding recruits transcription factors (TFs) to the genome to regulate gene expression. Here, we perform high resolution mapping of CEBP proteins to determine how sequence dictates genomic occupancy. We demonstrate a fundamental difference between the sequence repertoire utiliz...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Cohen, Daniel M, Lim, Hee-Woong, Won, Kyoung-Jae, Steger, David J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144830/
https://ncbi.nlm.nih.gov/pubmed/30085281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky681
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