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Shared nucleotide flanks confer transcriptional competency to bZip core motifs

Sequence-specific DNA binding recruits transcription factors (TFs) to the genome to regulate gene expression. Here, we perform high resolution mapping of CEBP proteins to determine how sequence dictates genomic occupancy. We demonstrate a fundamental difference between the sequence repertoire utiliz...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Cohen, Daniel M, Lim, Hee-Woong, Won, Kyoung-Jae, Steger, David J
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144830/
https://ncbi.nlm.nih.gov/pubmed/30085281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky681
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