Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions

The platelet receptors glycoprotein (Gp)VI, integrin α (2) β (1) and GpIb/V/IX mediate platelet adhesion and activation during thrombogenesis. Increases of intracellular Ca (2+) ([Ca (2+) ] (i) ) are key signals during platelet activation; however, their relative importance in coupling different col...

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Detalhes bibliográficos
Publicado no:Thromb Haemost
Main Authors: Pugh, Nicholas, Maddox, Ben D., Bihan, Dominique, Taylor, Kirk A., Mahaut-Smith, Martyn P., Farndale, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: Schattauer GmbH 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291897/
https://ncbi.nlm.nih.gov/pubmed/28536721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH16-12-0906
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