Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood

Exposed subendothelial collagen acts as a substrate for platelet adhesion and thrombus formation after vascular injury. Synthetic collagen-derived triple-helical peptides, designated collagen-related peptide (CRP), GFOGER, and VWF-III, can specifically engage the platelet collagen receptors, glycopr...

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Detalhes bibliográficos
Main Authors: Pugh, Nicholas, Simpson, Anna M. C., Smethurst, Peter A., de Groot, Philip G., Raynal, Nicolas, Farndale, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890152/
https://ncbi.nlm.nih.gov/pubmed/20351310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-260778
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