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Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure Degradation Relationships
The Immunomodulatory Drugs (IMiDs) Thalidomide, Pomalidomide and Lenalidomide have been approved for the treatment of multiple myeloma for many years. Recently, their usage as E3 ligase recruiting elements for small molecule induced protein degradation has led to a resurgence in interest in ImiD syn...
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| Publicado no: | ChemMedChem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291207/ https://ncbi.nlm.nih.gov/pubmed/29870139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800271 |
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