Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL

Proteolysis Targeting Chimera (PROTAC) technology is a rapidly emerging alternative therapeutic strategy with the potential to address many of the challenges currently faced in modern drug development programs. PROTAC technology employs small molecules that recruit target proteins for ubiquitination...

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Xehetasun bibliografikoak
Argitaratua izan da:Angew Chem Int Ed Engl
Egile Nagusiak: Lai, Ashton C., Toure, Momar, Hellerschmied, Doris, Salami, Jemilat, Jaime-Figueroa, Saul, Ko, Eunhwa, Hines, John, Crews, Craig M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733637/
https://ncbi.nlm.nih.gov/pubmed/26593377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507634
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