The Proximal Signaling Network of the BCR-ABL1 Oncogene Shows a Modular Organization

BCR-ABL1 is a fusion tyrosine-kinase, which causes multiple types of leukemia. We used an integrated proteomic approach that includes label-free quantitative protein complex and phosphorylation profiling by mass spectrometry to systematically characterize the proximal signaling network of this oncog...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Titz, Björn, Low, Tracey, Komisopoulou, Evangelia, Chen, Sharon S, Rubbi, Liudmilla, Graeber, Thomas G
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308218/
https://ncbi.nlm.nih.gov/pubmed/20697350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.331
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