Antimetastatic effect of epigenetic drugs, hydralazine and valproic acid, in Ras-transformed NIH 3T3 cells

INTRODUCTION: Metastasis involves the accumulation of genetic and epigenetic alterations leading to activation of prometastatic genes and inactivation of antimetastatic genes. Among epigenetic alterations, DNA hypermethylation and histone hypoacetylation are the focus of intense translational resear...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Main Authors: Pérez-Cárdenas, Enrique, Taja-Chayeb, Lucía, Trejo-Becerril, Catalina, Chanona-Vilchis, José, Chávez-Blanco, Alma, Domínguez-Gómez, Guadalupe, Langley, Elizabeth, García-Carrancá, Alejandro, Dueñas-González, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2018
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290866/
https://ncbi.nlm.nih.gov/pubmed/30584338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S187306
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