DNA Methylation-Independent Reversion of Gemcitabine Resistance by Hydralazine in Cervical Cancer Cells

BACKGROUND: Down regulation of genes coding for nucleoside transporters and drug metabolism responsible for uptake and metabolic activation of the nucleoside gemcitabine is related with acquired tumor resistance against this agent. Hydralazine has been shown to reverse doxorubicin resistance in a mo...

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Main Authors: Candelaria, Myrna, de la Cruz-Hernandez, Erick, Taja-Chayeb, Lucia, Perez-Cardenas, Enrique, Trejo-Becerril, Catalina, Gonzalez-Fierro, Aurora, Chavez-Blanco, Alma, Soto-Reyes, Ernesto, Dominguez, Guadalupe, Trujillo, Jaenai E., Diaz-Chavez, Jose, Duenas-Gonzalez, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299634/
https://ncbi.nlm.nih.gov/pubmed/22427797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029181
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