Antimetastatic effect of epigenetic drugs, hydralazine and valproic acid, in Ras-transformed NIH 3T3 cells

INTRODUCTION: Metastasis involves the accumulation of genetic and epigenetic alterations leading to activation of prometastatic genes and inactivation of antimetastatic genes. Among epigenetic alterations, DNA hypermethylation and histone hypoacetylation are the focus of intense translational resear...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Onco Targets Ther
Main Authors: Pérez-Cárdenas, Enrique, Taja-Chayeb, Lucía, Trejo-Becerril, Catalina, Chanona-Vilchis, José, Chávez-Blanco, Alma, Domínguez-Gómez, Guadalupe, Langley, Elizabeth, García-Carrancá, Alejandro, Dueñas-González, Alfonso
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290866/
https://ncbi.nlm.nih.gov/pubmed/30584338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S187306
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