Antimetastatic effect of epigenetic drugs, hydralazine and valproic acid, in Ras-transformed NIH 3T3 cells

INTRODUCTION: Metastasis involves the accumulation of genetic and epigenetic alterations leading to activation of prometastatic genes and inactivation of antimetastatic genes. Among epigenetic alterations, DNA hypermethylation and histone hypoacetylation are the focus of intense translational resear...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Pérez-Cárdenas, Enrique, Taja-Chayeb, Lucía, Trejo-Becerril, Catalina, Chanona-Vilchis, José, Chávez-Blanco, Alma, Domínguez-Gómez, Guadalupe, Langley, Elizabeth, García-Carrancá, Alejandro, Dueñas-González, Alfonso
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290866/
https://ncbi.nlm.nih.gov/pubmed/30584338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S187306
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