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Non-redundant roles of IL-21 and IL-4 in the phased initiation of germinal center B cells and subsequent self-renewal transitions
We examined the unique contributions of the cytokines IL-21 and IL-4 on germinal center (GC) B cell initiation and subsequent maturation in a murine model system. Similar to other reports, we found T follicular helper cell (Tfh) expression of IL-21 begins prior to Tfh migration into the B cell folli...
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出版年: | J Immunol |
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主要な著者: | , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2018
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6289626/ https://ncbi.nlm.nih.gov/pubmed/30446568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500497 |
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